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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85ab0b7df740c0bfd415fc931a63ee766b238beebf0d5685c6fad8f8f6a81007' 
  AND token = 'Ni95YTVtZomxplWBKkO46qvd1lPAkHxFM4rv9Z6JJg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}