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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7269ae460b9f5d93a6661bbab26a101edce0d201eccf82c9b67e9c29f4e08a' 
  AND token = 'Pc3ELZNReFrse3Ij8SfaFPl4zmQ1XBCDWwc5SrDOA2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}