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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dcadf3322968669b7cc3257667a488aa7274b18429e3ce40d6f28a388c5d226' 
  AND token = 'DG8lEpIXOwzXWJvsspHj587coRq3X8caaFAdbRLmwJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}