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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1fc94dfc6a004d751598915705f52af7d4e19b8420012b31da9014fb6571f0' 
  AND token = 'yHB8sS3VozrdTkyhG0ZVA8NydLHYLXuFd/3Orgc8mkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}