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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b06db3b0a84a1510ce46d06be1d58227b322c43e3da8c82e1e7ca14a6a954a6' 
  AND token = 'f47mSAIkdkVxuz+P1YpYFRsBqmFwiOKtCKLv1Q7EAX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}