SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7371f2eb8d3fe4075d7b6670725051d13969ebd104281f3d1a22dfd76986f817' 
  AND token = 'Gyo2dV3PPnSuAXIksqXuPcrAYU3qcBqh+ffMrwB1HBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}