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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac756d177b826e0b075b800d25df455bc9b213483b8dd81b984eaeb68d103072' 
  AND token = 'ADHODi9ixAXQcWnB7m+t0fDImnt9bW2m0GPWncRlubU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}