SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43f609cd9397f86865ce4d9bad3810a50b3fe0c686266706766ee3f9cf2fd30' 
  AND token = 'oWYClp+UPf30SEs4FVG4Vs3TEk+uOsET7PPA6sysz5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}