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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0daaf36b535fd5516d7f1a6f33f6fa08b8a7b7e11c3d4d09e2a11a211bb423c' 
  AND token = 'xaHr253fJRpg/TOVuZmRPg2iA05BNl9C0JjSYpSrT9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}