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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243424f6a2004b021b25eba8acbb5f33b8b67bf9c85304d5ee5749cf4fc99453' 
  AND token = 'KITbAXou2ouiRdoHjmR2eiSmJFdeB4SOWbEZVsHIlIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}