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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc9e2c6fe634837d98abb212d4fec37bc4d77e6d5b718b6b46411271f7b3ae7' 
  AND token = 'EI5dznWxjLL7EsZQ0NPe9ymdE3P4Zh0+VV8QF6LIc+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}