SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd606a19e00ce441398ecf22f634d06709ea9fdd48155e2b8fcd7f8a297caeae3' 
  AND token = 'ey2b7sZv7SQpFvrLMLrgbpim7VAjEUmUIBQ59UCZt08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}