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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183994f34a1aa7e9a507fbe9825940164a293196a7c6a14a731c29cc8fdb54a1' 
  AND token = '8F6FuxXhd7DXM85GfNlL7r6ZErCPNYiBVZwbiXQ5DZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}