SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4477c7a4eaa7456dda655b767c58078da8dcdc54c4dd2184b3386b6d4086482e' 
  AND token = '7hAe8W0ZywFgqwtam7iTtNx5X3DD4MMt5xKAUWWE+UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}