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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21ce290867abcef2558bc55b692def25f5ca95a513aa9c668377774263216d6' 
  AND token = 'wFz+dAyyE2J5Xz381DJ996BRahK/hC58XszjDNIyLeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}