SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7659cbca029a0d1eed0979b7b9e8b419e9091f90e66c3e5969e7655ca6c609' 
  AND token = 'FpbDaCbwPnqKxSONhb5GbKA4mwF1fJ5gNd2tC/Ih9n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}