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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bd520b5fe71ae1dd84009c015eea34b6379722b37c7db73fd50ced0c71e5f5' 
  AND token = 'xWPl95B+MQ9TP0uyslR5Dw5xoRg0sFlAwSVqu6AexkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}