SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a10c9ef00fc1d991da2f952cd7d19c31e8ed5b8b83aff8dbfcece122604054' 
  AND token = 'bQevUQSpIo05AoO6CUIqHbzw3Wo6a06cOiUYSeU/KAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}