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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c080b724403865a165a764452cf2e5d01c5f72b5e6cfb263e08ef0771a322c0' 
  AND token = '55EuIsX8bU0QY0nT0Z0x0v4wZhVOuYYBkYh0XVl7ZRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}