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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9434c5414dc8b10200130fba77cd880068a4c7290ec043540e9792dd355f3675' 
  AND token = '4QDYQ4e9bfdwKezioEDocE0PLdHsaT3QH1NCw4hu2vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}