SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a492ed5b365bd03bd452f5a1e621b92094a3967ca909f6f31941597b1c4b4788' 
  AND token = '0PwIHnOwzK8B3Yh5Kb9vcH6OrgtP7zUnF572buJA29Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}