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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff5059761e1c8f069c070759d8050ff070be212cf7e2729a5d873c1b152e2f09' 
  AND token = 'oj2TST8hzM4i5lyaZHHRuxfDAP4i/NDZE8HL8DHJYDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}