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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f618ea8f1d715c9555f059e7a1ede0539b79f7e53a2985caf143bd04a5847b' 
  AND token = 'POxgdr6vQqf8hU33diioAcVsSVp+rYkWq7RkOGqxzfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}