SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73de7dd458f11287434978327a8e86b19a3c9ebf47ce7b206b517ae725e5191' 
  AND token = 'JC2C5uVUbELHszMwf1laE8oeuMkFcJrDLtL1Qx5BvLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}