SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13e75d9da0179b9d696e7a89dc7f8a248a86b4eed9876b874aa7010e1f670a6' 
  AND token = 'K+21YRPjadh45YWeyA6hTuiGzOP3YL26l4qT/cgvGYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}