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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec7ea5e32504bf374979c883fb567d0820e0ed2ea4ae04541e27257e27ce202' 
  AND token = 'Mys/P9DpKXEyAzTMPUwotrz2/3ESNvOyDLvKa73bCKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}