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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3041168b8a4fdf41a6ad8698f55f7f93c38511c2d539be9e6c53153d8986a954' 
  AND token = '22nnAUBGCKepN4AXbnSKOqYWbgPaepwsCYlYkP1R+cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}