SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb5e73182238f430478ce9a8b369a3af455032a9bfa2f5705f2dc3ad52de821' 
  AND token = 'WrAYgYl1z5Lp/KYfZbE14NSS1YoeaunBjyPLnkP7Zbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}