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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85ed3d8b442216254f2631ab504db72c5111ea60dfb14c6f396c4177ac50cf2b' 
  AND token = 'EJxKQwl4vOeQUwvaYvxnLrdRjGPLpql4HtMlq4JK1CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}