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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e97de835c8e8aba2e00219c16e33dc8e6f0afda95604e23e0277d7ed8d343f' 
  AND token = 'nAD80lVxm2/EdlblDXrxDJW3Qij6MSxJdZYGDOmgwaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}