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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b016338a4f58656e40db626ce4249747f8abb15e6bcbe9de99b6005f0336a229' 
  AND token = 'LtpBzazUXzJOBQoC2k1bECo2FZkx20K/jbGP11bO1MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}