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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b225695f997f0fd3dd7720e1d40a787874772a7d17462eeaa8ea19f4234363' 
  AND token = 't4nqSO4qt7dU4BR1srEUlQ4hXLjd+J7sRl6vzOjbKd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}