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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '364a016f5a5bcbe81b3893a4d5e087b80b4e4044df4517f0e69db24089116eb7' 
  AND token = 'X5IIzGvOiX8kP8+XiKDCiEbz6lhfHyIBbGKUsqs9kZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}