SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4476ca6b77e9d08e01e7cd726520c32a9df7a29129813c4e5ec686dcaccb66c' 
  AND token = 'ZFPLTbIxg+/AQlhz706mpZxe9maK5WitrOs3mQdCB9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}