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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2444ce15561e4bd2ca655745951f4d3ad6c9cfad03de1fffa502b8e59b54284' 
  AND token = 'pu0dYhSI6Wlb8N/tWx0+xfKZPJWQHJH8R1zCJcj3xs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}