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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18eb49eaad06b0bfe36909801b71b334955399549cb9a5601cb60a597f3eabef' 
  AND token = 'dVa84/C7QJEucSOpYVeb8+6k3SSqXj9xFvovbwD9D44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}