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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '763933f140f918136d6d19a084094c01c3e01274c252487e0fd14ca02f909da7' 
  AND token = 'GAupive7400G+OL4iR7AquTWzTgtQRkHQNn2hvqhaY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}