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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a8f85493dd0e4866ad2ca44d56d1abb70f5931f14944581cdf656f8723ac49' 
  AND token = 'AYtY/ISatTmZSE+f17Oge42g2ynuKWPq5ESH/Ba9Lck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}