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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afee5e37aea701a33ff7f530a6b0982446a74160db26a786f79adfa60b8cacfc' 
  AND token = '9Vu63uG3AV9DRW/0JBJ4q8sdL0rHfaY8dkQI+OL/uwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}