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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e177bd81d8a0ee8253feecbfbcc042060ff2c1c613be4c95360ddba708d5211' 
  AND token = 'TF70T/V6v2ahB9KoOKnsXlbSL+pfGTTPoXj6o5jo8u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}