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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b751cd8775896e22f23d748fa7b257ab947c991ad3c1fb395e76b3ead36aee5c' 
  AND token = 'Af9UouOCVzT7s4ndi1Go/E/Fso7pKJcrFNmTXsOzlVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}