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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726656c06d4eed96fc668311462acb99c40e4ac37e0d8f9c0959715a61b879eb' 
  AND token = '270Cwcrad48t0jyWCqlm5GRzLxjPtqhGpoZL1N1tLW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}