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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a10a3617b93e4045239fc363f8ae898c8a0514aa9b83e13427d26210db10c41' 
  AND token = '+QEpJTjYq9yN9hhZ0IiNG8KlRcIT19ammcDRa4lxrLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}