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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a6a84625e11a389ceaf50dee1966ea378ae78c726ede4a759474d78a41c4d9' 
  AND token = 'N4YoZKiO4u7Se6IZzw5RSMGGzDobJECMQUEyy86aTcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}