SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2910e2019215ac54fe367fe53f9917f10ce2109e875234560cff2849c09c98a9' 
  AND token = 'IKLoOhD8XpeLXTneFo1tkKRzi169C+Qljitl3dape4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}