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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5c56821d16893a34ecc59d2f2d6952afa3e6e21342baece2b22feacf5e5b17' 
  AND token = '6kVJ2Vd713L+i7bGoIvpYjLudLCdGC2N4WUrVSEmE4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}