SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601d62be6adef027f463ccfa31eeb34bb9364e8494d95c014a839f89a8f2b0ae' 
  AND token = 'ue6BDRlhd4WDkrgU9NYZKnxS15U5sK7LLNX1SP99sqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}