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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fbd6bfe9650b66f6bb8a9032235ec094f36e110de9fe5135e76cf43b970e4b6' 
  AND token = 'AmO8E8dCc0SKPD2SCw1Q7mNguq46UyZFZfTI2wx+pKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}