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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc09e99a3589be019a1f91f7bbe80b0ef081b1e53b19c22710fdcd6316f985a' 
  AND token = 'PiyMC5pnBI5sX7fI9Vn4zLvl8eNcVMIZdhEVA8E38Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}