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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fbdeaee4f1d31774b3fc7b5861861ea80a3cc5ff958e7c983dae50dfbedec2e' 
  AND token = '/7GMoCrYBTHmfsvzX/igv8KHmEeLVQ/MyWkmv2FZmAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}